Your Gut and Eczema.

The Relationship Between your Gut’s Microbiome and Eczema

Another study released in September 2015 is reinforcing the importance of a healthy gut, this time as it relates to eczema. The findings suggest that when you haven’t got enough of the good gut bacteria, it can exaggerate the inflammation that’s associated with eczema.

As we discussed in our recent article, (PROBIOTICS AND ALLERGIC SKIN (ECZEMA), gut bacteria are necessary for production of certain vitamins - like Vitamin K, the leading cause of Vitamin K deficiency is due to depletion of proper gut bacteria. Changes in our symbiotic gut bacteria, or “microbiome”, can play an important role not only in digestive diseases such as irritable or inflammatory bowel disease, but in systemic diseases such as autoimmune conditions, obesity, and even allergic conditions like eczema.

In this study, the microbial composition and diversity were analysed in stool samples of pregnant women during their pregnancy and from the infants at age 1 week, 1 month and 12 months. The study compared infants again who remained free of any allergic symptoms at 2.5 years of age.

The study showed that the good gut bacteria was lower at 1 week of age in infants developing IgE-associated eczema. This relationship persisted at 1 month. Mothers whose infants developed IgE-associated eczema had lower good bacteria (α-diversity of Bacteroidetes) although this was not seen later in their infants. At 1 year, the α-diversity of Actinobacteria was lower in infants with IgE-associated eczema.

The findings of the study suggest that the reduced relative abundance of the good gut bacteria is associated with exaggerated inflammatory responses and subsequent development of IgE-associated eczema. We’ll continue to watch these studies and evidence as it becomes available.